The creation of economic opportunities through the promotion and development of the Mediterranean circular economy is the essence of CLUSTER4GREEN. In a vast part of the region, the leverage potential of circular economy is still lagging, deeply affecting the capacity of green sectors to generate wealth and jobs. CLUSTER4GREEN will take on the legacy of several previous projects that paved the way for the adoption of sustainable models of development, based on the circular concept, in industries like textile, building or smart cities. It will continue the green path with the generation of a “Common MED Circular Economy Programme” aimed at supporting both the green entrepreneurs and the local authorities responsible for the creation of an adequate green business environment. Innovative and sustainable business models will be elaborated and presented to a wide number of enterprises during specific training and assistance activities. As a final step on the green way, sustainable investment alliances will be established forging Public-Private Partnerships at national and international scale: as a result, the project will contribute to the “greening” of several Mediterranean industrial sectors at pilot level.